Description
| Product Name: | Human MRPS28 Recombinant Protein |
| Product Code: | RPPB4009 |
| Size: | 20µg |
| Species: | Human |
| Target: | MRPS28 |
| Synonyms: | Mitochondrial Ribosomal Protein S28, MRPS35, 28S Ribosomal Protein S35, Mitochondrial, MRP-S28, MRP-S35, S28mt, S35mt, 28S Ribosomal Protein S28, Mitochondrial, Mitochondrial 28S Ribosomal Protein S35, HSPC007. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | MRPS28 protein solution (0.25mg/ml) containing 20mM Phosphate buffer saline (pH 8.0), 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSGSPKNVE SFASMLRHSP LTQMGPAKDK LVIGRIFHIV ENDLYIDFGG KFHCVCRRPE VDGEKYQKGT RVRLRLLDLE LTSRFLGATT DTTVLEANAV LLGIQESKDS RSKEEHHEK |
Mitochondrialribosomes (mitoribosomes) consist of a small 28S subunit and a large 39Ssubunit. Mitochondrial Ribosomal Protein S28, also known as MRPS28, is a proteincoding gene which encodes a 28S subunit protein which is known as mitochondrialribosomal protein S35.
MRPS28 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 139 amino acids (72-187a.a) and having a molecular mass of 15.5kDa. MRPS28 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MRPS28: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins. |
| UniProt Protein Details: | Protein type:Mitochondrial; Translation; RNA-binding; Ribosomal Chromosomal Location of Human Ortholog: 8q21.1-q21.2 Cellular Component: mitochondrion; mitochondrial small ribosomal subunit; mitochondrial inner membrane Biological Process: mitochondrial translation; organelle organization and biogenesis |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y2Q9 |
| NCBI GenInfo Identifier: | 22001973 |
| NCBI Gene ID: | 28957 |
| NCBI Accession: | Q9Y2Q9.1 |
| UniProt Secondary Accession: | Q9Y2Q9,Q96Q21, B2RDZ7, |
| UniProt Related Accession: | Q9Y2Q9 |
| Molecular Weight: | 187 |
| NCBI Full Name: | 28S ribosomal protein S28, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein S28 |
| NCBI Official Symbol: | MRPS28�� |
| NCBI Official Synonym Symbols: | MRPS35; HSPC007; MRP-S28; MRP-S35�� |
| NCBI Protein Information: | 28S ribosomal protein S28, mitochondrial; S28mt; S35mt; mitochondrial 28S ribosomal protein S35; 28S ribosomal protein S35, mitochondrial |
| UniProt Protein Name: | 28S ribosomal protein S28, mitochondrial |
| UniProt Synonym Protein Names: | 28S ribosomal protein S35, mitochondrial; MRP-S35; S35mt |
| Protein Family: | 28S ribosomal protein |
| UniProt Gene Name: | MRPS28�� |
| UniProt Entry Name: | RT28_HUMAN |
