Description
| Product Name: | Human METTL21A Recombinant Protein |
| Product Code: | RPPB1940 |
| Size: | 10µg |
| Species: | Human |
| Target: | METTL21A |
| Synonyms: | Protein N-lysine methyltransferase METTL21A, HSPA lysine methyltransferase, HSPA-KMT, Hepatocellular carcinoma-associated antigen 557b, Methyltransferase-like protein 21A, METTL21A, FAM119A, HCA557B, Methyltransferase Like 21A. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The METTL21A solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSTDRKVAL EFLKSNVQAN LPPHIQTKTV VKELTWGQNL GSFSPGEFDL ILGADIIYLE ETFTDLLQTL EHLCSNHSVI LLACRIRYER DNNFLAMLER QFTVRKVHYD PEKDVHIYEA QKRNQKEDL |
METTL21A, which is a part of the methyltransferase superfamily, is a Protein-lysine methyltransferase that in vitro methylates HSPA1, HSPA5 and HSPA8.
METTL21A Human Recombinant produced in E. coli is a single polypeptide chain containing 149 amino acids (93-218) and having a molecular mass of 17 kDa.METTL21A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | FAM119A: a methyltransferase of the METTL21 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; EC 2.1.1.-; Methyltransferase, protein lysineChromosomal Location of Human Ortholog: 2q33.3Cellular Component: cytoplasmMolecular Function: protein binding; protein-lysine N-methyltransferase activity; Hsp70 protein binding; ATPase bindingBiological Process: regulation of ATPase activity; protein amino acid methylation; peptidyl-lysine methylation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8WXB1 |
| NCBI GenInfo Identifier: | 14495701 |
| NCBI Gene ID: | 151194 |
| NCBI Accession: | AAH09462.1 |
| UniProt Secondary Accession: | Q8WXB1,Q53RV0, Q8N1Z9, Q96GH6 |
| UniProt Related Accession: | Q8WXB1 |
| Molecular Weight: | |
| NCBI Full Name: | FAM119A protein |
| NCBI Synonym Full Names: | methyltransferase like 21A |
| NCBI Official Symbol: | METTL21A�� |
| NCBI Official Synonym Symbols: | FAM119A; HCA557b; HSPA-KMT�� |
| NCBI Protein Information: | protein N-lysine methyltransferase METTL21A; HSPA lysine methyltransferase; family with sequence similarity 119, member A; heat shock protein 70kDa lysine (K) methyltransferase; hepatocellular carcinoma-associated antigen 557b; methyltransferase-like protein 21A; protein-lysine methyltransferase METTL21A |
| UniProt Protein Name: | Protein N-lysine methyltransferase METTL21A |
| UniProt Synonym Protein Names: | HSPA lysine methyltransferase; HSPA-KMT; Hepatocellular carcinoma-associated antigen 557b; Methyltransferase-like protein 21A |
| Protein Family: | |
| UniProt Gene Name: | METTL21A�� |
| UniProt Entry Name: | MT21A_HUMAN |
