Description
| Product Name: | Human IL1F10 Recombinant Protein |
| Product Code: | RPPB0689 |
| Size: | 10µg |
| Species: | Human |
| Target: | IL1F10 |
| Synonyms: | Interleukin-1 family member 10, IL-1F10, FIL1 theta, Interleukin-1 HY2, IL-1HY2, Interleukin-1 theta, IL-1 theta, IL1F10, FIL1T, IL1HY2, FKSG75, MGC119831, MGC119832, MGC119833, FIL1-theta. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | IL1F10 was lyophilized after extensive dialysis against 20mM Phosphate buffer, pH7.4. |
| Solubility: | It is recommended to quick spin followed by reconstitution of IL1F10 in PBS to a concentration no less than 100 �g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized IL1F10 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL1F10 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Cys-Ser-Leu-Pro |
| Biological Activity: | As measured by its binding ability in a functional ELISA, immobilized IL1F10 at 1 �g/ml (100 �l/well) can bind rHuIL-1 Rrp2/Fc Chimera with a linear range of 0.15- 5 �g/ml. |
Human interleukin family 1, member 10 (IL1F10) belongs to the interleukin 1 cytokine family. IL1F10 is expressed in the fetal skin, spleen and tonsil, generally in the basal epithelia of skin and in proliferating B-cells of the tonsil. IL1F10 binds soluble IL1 receptor type 1 and may be implicated in the regulation of adapted and innate immune responses.
IL1F10 Human Recombinant produced in E.Coli is a single,�non-glycosylated, Polypeptide chain containing 152 amino acids and having a molecular mass of 17kDa.The IL1F10 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | IL1F10: Binds soluble IL-1 receptor type 1. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytokine Chromosomal Location of Human Ortholog: 2q13 Cellular Component: extracellular space Molecular Function:interleukin-1 receptor binding; cytokine activity Biological Process: cytokine and chemokine mediated signaling pathway |
| NCBI Summary: | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WWZ1 |
| NCBI GenInfo Identifier: | 25008589 |
| NCBI Gene ID: | 84639 |
| NCBI Accession: | Q8WWZ1.1 |
| UniProt Secondary Accession: | Q8WWZ1,Q53SR9, Q56AT8, Q7RTZ5, Q969H5, Q9BYX1, |
| UniProt Related Accession: | Q8WWZ1 |
| Molecular Weight: | 16,943 Da |
| NCBI Full Name: | Interleukin-1 family member 10 |
| NCBI Synonym Full Names: | interleukin 1 family, member 10 (theta) |
| NCBI Official Symbol: | IL1F10�� |
| NCBI Official Synonym Symbols: | IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta�� |
| NCBI Protein Information: | interleukin-1 family member 10; FIL1 theta; IL-1 theta; interleukin-38; interleukin-1 HY2; family of interleukin 1-theta; IL-1F10 (canonical form IL-1F10a); interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta |
| UniProt Protein Name: | Interleukin-1 family member 10 |
| UniProt Synonym Protein Names: | Family of interleukin 1-theta; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta; Interleukin-38 |
| UniProt Gene Name: | IL1F10�� |
| UniProt Entry Name: | IL1FA_HUMAN |
