Description
| Product Name: | Human IFT20 Recombinant Protein |
| Product Code: | RPPB3737 |
| Size: | 20µg |
| Species: | Human |
| Target: | IFT20 |
| Synonyms: | Intraflagellar Transport 20 Homolog (Chlamydomonas), Intraflagellar Transport Protein IFT20, HIFT20. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The IFT20 solution�contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 30% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAKDILGEAG LHFDELNKLR VLDPEVTQQT IELKEECKDF VDKIGQFQKI VGGLIELVDQ LAKEAENEKM KAIGARNLLK SIAKQREAQQ QQLQALIAEK KMQLERYRVE YEALCKVEAE QNEFIDQFIF QK |
IFT20 is a fragment of intraflagellar transport (IFT) elements which takes part in ciliary process assembly. IFT20 is involved in the transferring of ciliary membrane proteins from the Golgi complex to the cilium and is expressed in virtually all tissues.
IFT20 Human Recombinant produced in E. coli is a single polypeptide chain containing 152 amino acids (1-132) and having a molecular mass of 17.0 kDa.IFT20 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | IFT20: Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 17q11.2Cellular Component: centrosome; cis-Golgi network; Golgi membraneMolecular Function: protein bindingBiological Process: cilium biogenesis; protein localization in Golgi apparatus |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components (Finetti et al., PubMed: 19855387). This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.[provided by RefSeq, Jun 2012] |
| UniProt Code: | Q8IY31 |
| NCBI GenInfo Identifier: | 74728279 |
| NCBI Gene ID: | 90410 |
| NCBI Accession: | Q8IY31.1 |
| UniProt Secondary Accession: | Q8IY31,Q5GLZ2, Q9BUG5, J3QL09 |
| UniProt Related Accession: | Q8IY31 |
| Molecular Weight: | 12,969 Da |
| NCBI Full Name: | Intraflagellar transport protein 20 homolog |
| NCBI Synonym Full Names: | intraflagellar transport 20 |
| NCBI Official Symbol: | IFT20�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | intraflagellar transport protein 20 homolog |
| UniProt Protein Name: | Intraflagellar transport protein 20 homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | Intraflagellar transport protein |
| UniProt Gene Name: | IFT20�� |
| UniProt Entry Name: | IFT20_HUMAN |
