Description
| Product Name: | Human HAPLN1 Recombinant Protein |
| Product Code: | RPPB3654 |
| Size: | 10µg |
| Species: | Human |
| Target: | HAPLN1 |
| Synonyms: | Hyaluronan and proteoglycan link protein 1 precursor, CRTL1, Cartilage-linking protein 1, Cartilage-link protein, Proteoglycan link protein, HAPLN1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | HAPLN1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 80.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSDHLSDNY TLDHDRAIHI QAENGPHLLV EAEQAKVFSH RGGNVTLPCK FYRDPTAFGS GIHKIRIKWT KLTSDYLKEV DVFVSMGYHK KTYGGYQGRV FLKGGSDSDA SLVITDLTLE DYGRYKCEVI EGLEDDTVVV ALDLQGVVFP YFPRLGRYNL NFHEAQQACL DQDAVIASFD QLYDAWRGGL DWCNAGWLSD GSVQYPITKP REPCGGQNTV PGVRNYGFWD KDKSRYDVFC FTSNFNGRFY YLIHPTKLTY DEAVQACLND GAQIAKVGQI FAAWKILGYD RCDAGWLADG SVRYPISRPR RRCSPTEAAV RFVGFPDKKH KLYGVYCFRA YN |
Hyaluronan And Proteoglycan Link Protein 1, which is also known as HAPLN1 is a part of the HAPLN family.HAPLN1 contains one Ig-like V-type domain and two Link domains. In the extracellular cartilage matrix, HAPLN1 stabilizes the aggregates of proteoglycan monomers by means of hyaluronic acid .
HAPLN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 362 amino acids (16-354 a.a.) and having a molecular mass of 40.9kDa.HAPLN1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | HAPLN1: Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix. Belongs to the HAPLN family. |
| UniProt Protein Details: | Protein type:Extracellular matrix Chromosomal Location of Human Ortholog: 5q14.3 Cellular Component: extracellular matrix; extracellular region; proteinaceous extracellular matrix Molecular Function:extracellular matrix structural constituent; hyaluronic acid binding Biological Process: central nervous system development; extracellular matrix organization and biogenesis; skeletal development |
| UniProt Code: | P10915 |
| NCBI GenInfo Identifier: | 130310 |
| NCBI Gene ID: | 1404 |
| NCBI Accession: | P10915.2 |
| UniProt Secondary Accession: | P10915,B2R9A9, |
| UniProt Related Accession: | P10915 |
| Molecular Weight: | 40kDa |
| NCBI Full Name: | Hyaluronan and proteoglycan link protein 1 |
| NCBI Synonym Full Names: | hyaluronan and proteoglycan link protein 1 |
| NCBI Official Symbol: | HAPLN1�� |
| NCBI Official Synonym Symbols: | CRT1; CRTL1�� |
| NCBI Protein Information: | hyaluronan and proteoglycan link protein 1 |
| UniProt Protein Name: | Hyaluronan and proteoglycan link protein 1 |
| UniProt Synonym Protein Names: | Cartilage-linking protein 1; Cartilage-link protein; Proteoglycan link protein |
| Protein Family: | Hyaluronan and proteoglycan link protein |
| UniProt Gene Name: | HAPLN1�� |
