Description
| Product Name: | Human FAM3D Recombinant Protein |
| Product Code: | RPPB3511 |
| Size: | 10µg |
| Species: | Human |
| Target: | FAM3D |
| Synonyms: | Protein FAM3D, FAM3D, EF7, OIT1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | FAM3D filtered (0.4 �m) and lyophilized from 0.5mg/ml in 0.05M Acetate buffer pH-4.0. |
| Solubility: | It is recommended to add 200�l of 0.1M Acetate buffer pH-4 to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely at 37�C. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10�g/ml. In higher concentrations the solubility of this antigen is limited. FAM3D is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. |
| Stability: | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MKHHHHHHASYMSFSMKTIR LPRWLAASPT KEIQVKKYKC GLIKPCPANY FAFKICSGAA NVVGPTMCFE DRMIMSPVKN NVGRGLNIAL VNGTTGAVLG QKAFDMYSGD VMHLVKFLKE IPGGALVLVA SYDDPGTKMN DESRKLFSDL GSSYAKQLGF RDSWVFIGAK DLRGKSPFEQ FLKNSPDTNK YEGWPELLEM EGCMPPKPF |
Family with Sequence Similarity 3, Member D (FAM3D) is a member of the FAM3 family. The FAM3D gene is linked to narcolepsy and diabetes mellitus in pancreatic adenocarcinoma, however FAM3D function of remains vague. FAM3D is amply expressed in the placenta and weakly expressed in the small intestine.
FAM3D Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 26-224) containing 209 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 23.3kDa (calculated).
| UniProt Protein Function: | FAM3D: Belongs to the FAM3 family. |
| UniProt Protein Details: | Protein type:Cytokine; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 3p14.2 Cellular Component: extracellular region Molecular Function:cytokine activity Biological Process: negative regulation of insulin secretion |
| UniProt Code: | Q96BQ1 |
| NCBI GenInfo Identifier: | 20270363 |
| NCBI Gene ID: | 131177 |
| NCBI Accession: | NP_620160.1 |
| UniProt Secondary Accession: | Q96BQ1,Q547G2, |
| UniProt Related Accession: | Q96BQ1 |
| Molecular Weight: | 24,963 Da |
| NCBI Full Name: | family with sequence similarity 3, member D |
| NCBI Synonym Full Names: | family with sequence similarity 3, member D |
| NCBI Official Symbol: | FAM3D�� |
| NCBI Official Synonym Symbols: | EF7; OIT1�� |
| NCBI Protein Information: | family with sequence similarity 3, member D; OTTHUMP00000214165; OTTHUMP00000214166; cytokine-like protein EF-7 |
| UniProt Protein Name: | Protein FAM3D |
| Protein Family: | Protein |
| UniProt Gene Name: | FAM3D�� |
| UniProt Entry Name: | FAM3D_HUMAN |
