Description
| Product Name: | Human EEF1G Recombinant Protein |
| Product Code: | RPPB3398 |
| Size: | 20µg |
| Species: | Human |
| Target: | EEF1G |
| Synonyms: | EF1G, GIG35, Elongation factor 1-gamma, Eukaryotic Translation Elongation Factor 1 Gamma, EEF1G, EF-1-gamma, eEF-1B gamma, PRO1608. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The EEF1G solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAAGTLY TYPENWRAFK ALIAAQYSGA QVRVLSAPPH FHFGQTNRTP EFLRKFPAGK VPAFEGDDGF CVFESNAIAY YVSNEELRGS TPEAAAQVVQ WVSFADSDIV PPASTWVFPT LGIMHHNKQA TENAKEEVRR ILGLLDAYLK TRTFLVGERV TLADITVVCT LLWLYKQVLE PSFRQAFPNT NRWFLTCINQ PQFRAVLGEV KLCEKMAQFD AKKFAETQPK KDTPRKEKGS REEKQKPQAE RKEEKKAAAP APEEEMDECE QALAAEPKAK DPFAHLPKST FVLDEFKRKY SNEDTLSVAL PYFWEHFDKD GWSLWYSEYR FPEELTQTFM SCNLITGMFQ RLDKLRKNAF ASVILFGTNN SSSISGVWVF RGQELAFPLS PDWQVDYESY TWRKLDPGSE ETQTLVREYF SWEGAFQHVG KAFNQGKIFK |
Eukaryotic Translation Elongation Factor 1 Gamma (EEF1G) takes part in anchoring the complex to additional cellular components. EEF1G is a multi-protein complex which is in charge of the delivery of aminoacyl-tRNAs to the ribosome. Over expression of EEF1G is linked with pancreatic cancer, due to the role of EEF1G protein in the oncogenic transformation process.
EEF1G Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 460 amino acids (1-437) and having a molecular mass of 52.5 kDa.EEF1G is fused to a 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | EEF1G: Probably plays a role in anchoring the complex to other cellular components. |
| UniProt Protein Details: | Protein type:Translation; Translation elongation Chromosomal Location of Human Ortholog: 11q12.3 Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; membrane; nucleus Molecular Function:cadherin binding; protein binding Biological Process: response to virus; translational elongation |
| NCBI Summary: | This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P26641 |
| NCBI GenInfo Identifier: | 119165 |
| NCBI Gene ID: | 1937 |
| NCBI Accession: | P26641.3 |
| UniProt Secondary Accession: | P26641,Q6PJ62, Q6PK31, Q96CU2, Q9P196, B4DTG2, |
| UniProt Related Accession: | P26641 |
| Molecular Weight: | 50kDa |
| NCBI Full Name: | Elongation factor 1-gamma |
| NCBI Synonym Full Names: | eukaryotic translation elongation factor 1 gamma |
| NCBI Official Symbol: | EEF1G�� |
| NCBI Official Synonym Symbols: | EF1G; GIG35�� |
| NCBI Protein Information: | elongation factor 1-gamma |
| UniProt Protein Name: | Elongation factor 1-gamma |
| UniProt Synonym Protein Names: | eEF-1B gamma |
| Protein Family: | Elongation factor |
| UniProt Gene Name: | EEF1G�� |
