Description
| Product Name: | Human DYNLRB2 Recombinant Protein |
| Product Code: | RPPB3382 |
| Size: | 20µg |
| Species: | Human |
| Target: | DYNLRB2 |
| Synonyms: | Dynein light chain roadblock-type 2, Dynein light chain 2B cytoplasmic, Roadblock domain-containing protein 2, DYNLRB2, DNCL2B, DNLC2B, ROBLD2, MGC62033. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The DYNLRB2 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAEVEETLKR IQSHKGVIGT MVVNAEGIPI RTTLDNSTTV QYAGLLHHLT MKAKSTVRDI DPQNDLTFLR IRSKKHEIMV APDKEYLLIV IQNPCE |
Dynein light chain roadblock-type 2 (DYNLRB2) functions as one of several non-catalytic accessory components of the cytoplasmic dynein complex which are considered to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein functions as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
DYNLRB2 Human Recombinant fused with a�20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing�116 amino acids (1-96 a.a.) and having a molecular mass of 13kDa. The DYNLRB2 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | DYNLRB2: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Belongs to the GAMAD family.Protein type: Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 16q23.3Cellular Component: microtubule; cytoplasmic dynein complexMolecular Function: microtubule motor activityBiological Process: metabolic process; transport; organelle organization and biogenesis; microtubule-based movement |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TF09 |
| NCBI GenInfo Identifier: | 18702323 |
| NCBI Gene ID: | 83657 |
| NCBI Accession: | NP_570967.1 |
| UniProt Secondary Accession: | Q8TF09 |
| UniProt Related Accession: | Q8TF09 |
| Molecular Weight: | |
| NCBI Full Name: | dynein light chain roadblock-type 2 isoform 1 |
| NCBI Synonym Full Names: | dynein light chain roadblock-type 2 |
| NCBI Official Symbol: | DYNLRB2�� |
| NCBI Official Synonym Symbols: | DNCL2B; DNLC2B; ROBLD2�� |
| NCBI Protein Information: | dynein light chain roadblock-type 2 |
| UniProt Protein Name: | Dynein light chain roadblock-type 2 |
| UniProt Synonym Protein Names: | Dynein light chain 2B, cytoplasmic; Roadblock domain-containing protein 2 |
| Protein Family: | |
| UniProt Gene Name: | DYNLRB2�� |
| UniProt Entry Name: | DLRB2_HUMAN |
