Description
| Product Name: | Nanodisc Human DRD1 Protein |
| SKU: | HDFP220 |
| Size: | 10μg |
| Target: | DRD1 |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | DADR, DRD1A |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human DRD1 full length protein-synthetic nanodisc |
| Protein Pathways: | GPCRDB Class A Rhodopsin-like, Monoamine GPCRs, G-Protein Coupled Receptors Signaling Pathway. |
| Molecular Weight: | The human full length DRD1 protein has a MW of 49.3kDa |
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
| Uniprot ID: | P21728 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
