Description
| Product Name: | Human DLL3 Protein, His Tag |
| Product Code: | HDPT0493 |
| Size: | 50 µg |
| Alias: | SCDO1 |
| Target: | DLL3 |
| Tag: | C-6×His Tag |
| Expression Host: | HEK293 |
| Molecular Characterization: | DLL3(Ala27-Arg490) 6×His tag |
| Molecular Weight: | The protein has a predicted molecular mass of 49.1 kDa after removal of the signal peptide. The apparent molecular mass of DLL3-His is approximately 55-70 kDa due to glycosylation. |
| Purity: | The purity of the protein is greater than 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background: | This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. |
| Usage: | Research use only |