Description
| Product Name: | Human CUTA Recombinant Protein |
| Product Code: | RPPB3313 |
| Size: | 25µg |
| Species: | Human |
| Target: | CUTA |
| Synonyms: | ACHAP, C6orf82, MGC111154, cutA divalent cation tolerance homolog, CUTA. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | CUTA Human solution containing 20mM Tris-HCl pH-8, 1mM DTT, and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MRLLLLPRVL LTMASGSPPT QPSPASDSGS GYVPGSVSAA FVTCPNEKVA KEIARAVVEK RLAACVNLIP QITSIYEWKG KIEEDSEVLM MIKTQSSLVP ALTDFVRSVH PYEVAEVIAL PVEQGNFPYL QWVRQVTESV SDSITVLPLE HHHHHH |
CUTA is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. CUTA participates in cellular tolerance to a broad range of divalent cations other than copper. The CUTA protein is a cytoplasmic protein, encoded by the single-gene operon and has been related to divalent cation tolerance.
CUTA Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 156 amino acids (33-179 a.a.) and having a molecular mass of 17.1 kDa. CUTA protein is fused to an 8 amino acid His-Tag at C-terminus and purified by standard chromatography.
| UniProt Protein Function: | CUTA: May form part of a complex of membrane proteins attached to acetylcholinesterase (AChE). Belongs to the CutA family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 6p21.32 Cellular Component: membrane Molecular Function:protein binding; enzyme binding Biological Process: response to metal ion; protein localization |
| UniProt Code: | O60888 |
| NCBI GenInfo Identifier: | 62286491 |
| NCBI Gene ID: | 51596 |
| NCBI Accession: | O60888.2 |
| UniProt Secondary Accession: | O60888,Q3B784, Q5JXM9, Q5SU05, Q9NYQ9, A2AB26, A2BEL4 |
| UniProt Related Accession: | O60888 |
| Molecular Weight: | 179 |
| NCBI Full Name: | Protein CutA |
| NCBI Synonym Full Names: | cutA divalent cation tolerance homolog (E. coli) |
| NCBI Official Symbol: | CUTA�� |
| NCBI Official Synonym Symbols: | ACHAP; C6orf82�� |
| NCBI Protein Information: | protein CutA; divalent cation tolerant protein CUTA; acetylcholinesterase-associated protein; brain acetylcholinesterase putative membrane anchor |
| UniProt Protein Name: | Protein CutA |
| UniProt Synonym Protein Names: | Acetylcholinesterase-associated protein; Brain acetylcholinesterase putative membrane anchor |
| Protein Family: | Cutinase |
| UniProt Gene Name: | CUTA�� |
| UniProt Entry Name: | CUTA_HUMAN |
