Description
| Product Name: | Human CNRIP1 Recombinant Protein |
| Product Code: | RPPB3221 |
| Size: | 20µg |
| Species: | Human |
| Target: | CNRIP1 |
| Synonyms: | Cannabinoid Receptor Interacting Protein 1, Cannabinoid Receptor CB1-Interacting Protein 1, Chromosome 2 Open Reading Frame 32, C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CNRIP1 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 1mM DTT and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMGDLPGL VRLSIALRIQ PNDGPVFYKV DGQRFGQNRT IKLLTGSSYK VEVKIKPSTL QVENISIGGV LVPLELKSKE PDGDRVVYTG TYDTEGVTPT KSGERQPIQI TMPFTDIGTF ETVWQVKFYN YHKRDHCQWG SPFSVIEYEC KPNETRSLMW VNKESFL |
CB1 cannabinoid receptor-interacting protein 1 (CNRIP1) is a 164 amino acid protein and G-protein coupled receptor which is a member of the CNRIP family. The CNRIP1 interacts with the C-terminal tail of cannabinoid receptor 1. CNRIP1 is expressed in the brain tissue and, at low levels, in the testis. CNRIP1 is involved in appetite, synaptic plasticity, neuroprotection and analgesia.
CNRIP1 Human Recombinant produced in E. coli is a single polypeptide chain containing 187 amino acids (1-164) and having a molecular mass of 21.0 kDa.CNRIP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CNRIP1: Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect. Belongs to the CNRIP family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2p14Cellular Component: myelin sheath |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that interacts with the C-terminal tail of cannabinoid receptor 1. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q96F85 |
| NCBI GenInfo Identifier: | 68565256 |
| NCBI Gene ID: | 25927 |
| NCBI Accession: | Q96F85.1 |
| UniProt Secondary Accession: | Q96F85,Q49AN4, Q9UFZ0, B2R4D0 |
| UniProt Related Accession: | Q96F85 |
| Molecular Weight: | 14,224 Da |
| NCBI Full Name: | CB1 cannabinoid receptor-interacting protein 1 |
| NCBI Synonym Full Names: | cannabinoid receptor interacting protein 1 |
| NCBI Official Symbol: | CNRIP1�� |
| NCBI Official Synonym Symbols: | CRIP1; C2orf32�� |
| NCBI Protein Information: | CB1 cannabinoid receptor-interacting protein 1 |
| UniProt Protein Name: | CB1 cannabinoid receptor-interacting protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | CB1 cannabinoid receptor-interacting protein |
| UniProt Gene Name: | CNRIP1�� |
| UniProt Entry Name: | CNRP1_HUMAN |
