Description
system_update_altDatasheet
| Product name | Human CLDN4 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP064 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | CLDN4 |
| Uniprot: | O14493 |
| Description: | Human CLDN4 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length CLDN4 protein has a MW of 22.1 kDa |
| Protein Family: | Druggable Genome, Transmembrane |
| Protein Pathways: | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | CPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013] |
| Delivery: | 3-4 weeks |
| Usage | Research use only |
