Description
| Product Name: | Human CEBP Gamma Recombinant Protein |
| Product Code: | RPPB3141 |
| Size: | 50µg |
| Species: | Human |
| Target: | CEBP Gamma |
| Synonyms: | CCAAT/enhancer-binding protein gamma, C/EBP gamma, CEBPG, GPE1BP, IG/EBP-1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The protein contains 20mM Tris-HCl pH7.5, 0.1M NaCl and 5mM b-Mercaptoethanol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMPGG GGKAVAPSKQ SKKSSPMDRN SDEYRQRRER NNMAVKKSRL KSKQKAQDTL QRVNQLKEEN ERLEAKIKLL TKELSVLKDL FLEHAHNLAD NVQSISTENT TADGDN |
CCAAT/enhancer binding protein(C/EBP) g is a family of transcription factors all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP a,b,g,d, that form homodimers and/or form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBP g may cooperate with Fos to bind PRE- enhancer elements.
CEBP-g Recombinant Human His-Tag fusion protein produced in E.Coli is a single, non-glycosylated polypeptide chain containing amino acids 146 (aa 39-147) and having a molecular mass of 16.5 kDa. The DNA binding domain of CEBP-g was purified by proprietary chromatographic techniques.
| UniProt Protein Function: | C/EBP-gamma: Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites. Belongs to the bZIP family. C/EBP subfamily. |
| UniProt Protein Details: | Protein type:DNA-binding; Motility/polarity/chemotaxis; Transcription factor Chromosomal Location of Human Ortholog: 19q13.11 Cellular Component: nucleoplasm; nucleus Molecular Function:DNA binding; protein binding; protein heterodimerization activity; sequence-specific DNA binding; transcription factor binding Biological Process: B cell differentiation; enucleate erythrocyte differentiation; immune response; liver development; mRNA metabolic process; natural killer cell mediated cytotoxicity; negative regulation of transcription factor activity; positive regulation of DNA binding; positive regulation of DNA repair; positive regulation of interferon-gamma biosynthetic process; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter |
| NCBI Summary: | The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011] |
| UniProt Code: | P53567 |
| NCBI GenInfo Identifier: | 1705750 |
| NCBI Gene ID: | 1054 |
| NCBI Accession: | P53567.1 |
| UniProt Secondary Accession: | P53567,Q5U052, B2R946, |
| UniProt Related Accession: | P53567 |
| Molecular Weight: | 16,408 Da |
| NCBI Full Name: | CCAAT/enhancer-binding protein gamma |
| NCBI Synonym Full Names: | CCAAT/enhancer binding protein gamma |
| NCBI Official Symbol: | CEBPG�� |
| NCBI Official Synonym Symbols: | GPE1BP; IG/EBP-1�� |
| NCBI Protein Information: | CCAAT/enhancer-binding protein gamma |
| UniProt Protein Name: | CCAAT/enhancer-binding protein gamma |
| Protein Family: | CCAAT/enhancer-binding protein |
| UniProt Gene Name: | CEBPG�� |
| UniProt Entry Name: | CEBPG_HUMAN |
