Description
| Product Name: | Human CDC123 Recombinant Protein |
| Product Code: | RPPB3122 |
| Size: | 20µg |
| Species: | Human |
| Target: | CDC123 |
| Synonyms: | C10orf7, D123, Cell division cycle protein 123 homolog, ProteinD123, HT-1080, PZ32, Chromosome 10 Open Reading Frame 7. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CDC123 protein solution (0. 5mg/ml) containing 20mMTris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 2mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMKKEHVL HCQFSAWYPF FRGVTIKSVI LPLPQNVKDY LLDDGTLVVSGRDDPPTHSQ PDSDDEAEEI QWSDDENTAT LTAPEFPEFA TKVQEAINSL GGSVFPKLNW SAPRDAYWIAMNSSLKCKTL SDIFLLFKSS DFITRDFTQP FIHCTDDSPD PCIEYELVLR KWCELIPGAE FRCFVKENKL IGISQRDYTQ YYDHISKQKEEIRRCIQDFF KKHIQYKFLD EDFVFDIYRD SRGKVWLIDF NPFGEVTDSL LFTWEELISE NNLNGDFSEVDAQEQDSPAF RCTNSEVTVQ PSPYLSYRLP KDFVDLSTGE DAHKLIDFLK LKRNQQEDD |
CDC123is a member of the CDC123 family. CDC123 is required for S phase entry of the cell cycle. It is also broadly expressed in spleen, thymus, prostate,testis, ovary, small intestine, colon and leukocytes with the uppermost expressionin testis.
CDC123 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 359 amino acids (1-336 a.a) and having a molecular mass of 41.5kDa.CDC123 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CDC123: Required for S phase entry of the cell cycle. Belongs to the CDC123 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 10p14-p13 Cellular Component: cytoplasm Biological Process: cell cycle arrest; positive regulation of cell proliferation; positive regulation of translational initiation; regulation of translation |
| UniProt Code: | O75794 |
| NCBI GenInfo Identifier: | 74739631 |
| NCBI Gene ID: | 8872 |
| NCBI Accession: | O75794.1 |
| UniProt Secondary Accession: | O75794,Q14107, Q5T0L4, Q5T0L5, Q5T0L7, Q5T0L8, Q5T0L9 A8JZZ7, |
| UniProt Related Accession: | O75794 |
| Molecular Weight: | 39kDa |
| NCBI Full Name: | Cell division cycle protein 123 homolog |
| NCBI Synonym Full Names: | cell division cycle 123 |
| NCBI Official Symbol: | CDC123�� |
| NCBI Official Synonym Symbols: | D123; C10orf7�� |
| NCBI Protein Information: | cell division cycle protein 123 homolog |
| UniProt Protein Name: | Cell division cycle protein 123 homolog |
| UniProt Synonym Protein Names: | HT-1080; PZ32 |
| Protein Family: | Cell division cycle protein |
| UniProt Gene Name: | CDC123�� |
