Description
| Product Name: | Human BASP1 Recombinant Protein |
| Product Code: | RPPB2851 |
| Size: | 10µg |
| Species: | Human |
| Target: | BASP1 |
| Synonyms: | CAP-23, CAP23, NAP-22, NAP22, Brain acid soluble protein 1, BASP1, BASP1 Human, 22 kDa neuronal tissue-enriched acidic protein, Neuronal axonal membrane protein NAP-22. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The BASP1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMGGKLSK KKKGYNVNDE KAKEKDKKAE GAATEEEGTP KESEPQAAAE PAEAKEGKEK PDQDAEGKAE EKEGEKDAAA AKEEAPKAEP EKTEGAAEAK AEPPKAPEQE QAAPGPAAGG EAPKAAEAAA APAESAAPAA GEEPSKEEGE PKKTEAPAAP AAQETKSDGA PASDSKPGSS EAAPSSKETP AATEAPSSTP KAQGPAASAE EPKPVEAPAA NSDQTVTVKE |
Brain Abundant Membrane Attached Signal Protein 1 (BASP1) is a membrane bound protein with numerous transient phosphorylation positions and PEST motifs. Preservation of proteins with PEST sequences amongst diverse species supports their functional significance. PEST sequences take place in proteins with high turnover rates. Immunological attributes of this protein are species specific. BASP1 undergoes N-terminal myristoylation.
BASP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 250 amino acids (1-227) and having a molecular mass of 25 kDa (Molecular size on SDS-PAGE will appear higher). BASP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | BASP1: a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012] |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 5p15.1 Cellular Component: cell junction; cytoplasm; cytoskeleton; nuclear speck; nucleus; plasma membrane; signalosome; vesicle Molecular Function:protein binding; protein domain specific binding; transcription corepressor activity Biological Process: gonad development; negative regulation of transcription, DNA-dependent; substantia nigra development; thorax and anterior abdomen determination |
| NCBI Summary: | This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012] |
| UniProt Code: | P80723 |
| NCBI GenInfo Identifier: | 6686256 |
| NCBI Gene ID: | 10409 |
| NCBI Accession: | P80723.2 |
| UniProt Secondary Accession: | P80723,O43596, Q5U0S0, Q9BWA5, B4DJA8, D3DTD5, |
| UniProt Related Accession: | P80723 |
| Molecular Weight: | 23kDa |
| NCBI Full Name: | Brain acid soluble protein 1 |
| NCBI Synonym Full Names: | brain abundant membrane attached signal protein 1 |
| NCBI Official Symbol: | BASP1�� |
| NCBI Official Synonym Symbols: | CAP23; NAP22; CAP-23; NAP-22�� |
| NCBI Protein Information: | brain acid soluble protein 1 |
| UniProt Protein Name: | Brain acid soluble protein 1 |
| UniProt Synonym Protein Names: | 22 kDa neuronal tissue-enriched acidic protein; Neuronal axonal membrane protein NAP-22 |
| Protein Family: | Brain acid soluble protein |
| UniProt Gene Name: | BASP1�� |
