Description
| Product Name: | Human ATG5 Recombinant Protein |
| Product Code: | RPPB5845 |
| Size: | 10µg |
| Species: | Human |
| Target: | ATG5 |
| Synonyms: | Autophagy protein 5, APG5-like, Apoptosis-specific protein, ATG5, ASP, APG5, APG5L, hAPG5. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | ATG5 at a concentration of 0.25mg/ml containing 20mM Tris-HCl, pH 8.0, 1mM DTT , 0.2M NaCl and 40% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLPRVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNITVHFKSFPEK DLLHCPSKDA IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLKEVCPSAIDPE DGEKKNQVMI HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD |
ATG5 is a member of the autophagy-related (ATG) genes family. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. ATG5 protein is essential for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. In addition ATG5 takes a vital part in the apoptotic process and it is expressed relatively late in the apoptotic process, downstream of caspase activity.
ATG5 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 295 amino acids (1-275a.a.) and having a molecular mass of 34.6kDa.ATG5 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Code: | Q9H1Y0 |
| NCBI GenInfo Identifier: | 17366828 |
| NCBI Gene ID: | 9474 |
| NCBI Accession: | Q9H1Y0.2 |
| UniProt Secondary Accession: | Q9H1Y0,O60875, Q5JVR2, Q68DI4, Q9H2B8, Q9HCZ7, |
| UniProt Related Accession: | Q9H1Y0 |
| Molecular Weight: | 275 |
| NCBI Full Name: | Autophagy protein 5 |
| NCBI Synonym Full Names: | autophagy related 5 |
| NCBI Official Symbol: | ATG5�� |
| NCBI Official Synonym Symbols: | ASP; APG5; APG5L; hAPG5; APG5-LIKE�� |
| NCBI Protein Information: | autophagy protein 5; apoptosis-specific protein; ATG5 autophagy related 5 homolog |
| UniProt Protein Name: | Autophagy protein 5 |
| UniProt Synonym Protein Names: | APG5-like; Apoptosis-specific protein |
| Protein Family: | Autophagy protein |
| UniProt Gene Name: | ATG5�� |
| UniProt Entry Name: | ATG5_HUMAN |
