Description
| 抗体名: | HTATIP2 Antibody (PACO09837) |
| 抗体コード: | PACO09837 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human HTATIP2 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | 27kd; |
| UniProt Protein Function: | HTATIP2: Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Oxidoreductase; Apoptosis; Tumor suppressor; Nuclear envelope; Transcription factor; EC 1.1.1.- Chromosomal Location of Human Ortholog: 11p15.1 Cellular Component: membrane; cytoplasm; nuclear envelope; nucleus Molecular Function:protein binding; transcription coactivator activity; oxidoreductase activity Biological Process: regulation of transcription from RNA polymerase II promoter; viral reproduction; apoptosis; nuclear import; angiogenesis; cell differentiation; regulation of angiogenesis; negative regulation of apoptosis |
| UniProt Code: | Q9BUP3 |
| NCBI GenInfo Identifier: | 317373366 |
| NCBI Gene ID: | 10553 |
| NCBI Accession: | Q9BUP3.2 |
| UniProt Secondary Accession: | Q9BUP3,O15383, O60520, O95345, Q53GC1, Q53GG2, Q6IBI3 A8K7S7, D3DQY8, |
| UniProt Related Accession: | Q9BUP3 |
| Molecular Weight: | 242 |
| NCBI Full Name: | Oxidoreductase HTATIP2 |
| NCBI Synonym Full Names: | HIV-1 Tat interactive protein 2, 30kDa |
| NCBI Official Symbol: | HTATIP2 |
| NCBI Official Synonym Symbols: | CC3; TIP30; SDR44U1 |
| NCBI Protein Information: | oxidoreductase HTATIP2; Tat-interacting protein (30kD); HIV-1 TAT-interactive protein 2; 30 kDa HIV-1 TAT-interacting protein; short chain dehydrogenase/reductase family 44U, member 1 |
| UniProt Protein Name: | Oxidoreductase HTATIP2 |
| UniProt Synonym Protein Names: | 30 kDa HIV-1 TAT-interacting protein; HIV-1 TAT-interactive protein 2 |
| Protein Family: | Oxidoreductase |
| UniProt Gene Name: | HTATIP2 |
| UniProt Entry Name: | HTAI2_HUMAN |
