| UniProt Protein Function: | HOXB4: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Deformed subfamily. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 17q21.32 Biological Process: positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P17483 |
| NCBI GenInfo Identifier: | 547692 |
| NCBI Gene ID: | 3214 |
| NCBI Accession: | P17483.2 |
| UniProt Secondary Accession: | P17483,Q9NTA0, |
| UniProt Related Accession: | P17483 |
| Molecular Weight: | 27,604 Da |
| NCBI Full Name: | Homeobox protein Hox-B4 |
| NCBI Synonym Full Names: | homeobox B4 |
| NCBI Official Symbol: | HOXB4 |
| NCBI Official Synonym Symbols: | HOX2; HOX2F; HOX-2.6 |
| NCBI Protein Information: | homeobox protein Hox-B4 |
| UniProt Protein Name: | Homeobox protein Hox-B4 |
| UniProt Synonym Protein Names: | Homeobox protein Hox-2.6; Homeobox protein Hox-2F |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | HOXB4 |
