Description
| 抗体名: | HEPACAM2 Antibody, Biotin conjugated (PACO27352) |
| 抗体コード: | PACO27352 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human HEPACAM family member 2 protein (32-351AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. |
| シノニム: | HEPACAM family member 2 (Mitotic kinetics regulator), HEPACAM2, MIKI |
| UniProt Protein Function: | HEPACAM2: Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7q21.3Cellular Component: centrosome; Golgi apparatus; midbody; spindleMolecular Function: protein bindingBiological Process: centrosome organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A8MVW5 |
| NCBI GenInfo Identifier: | 187659944 |
| NCBI Gene ID: | 253012 |
| NCBI Accession: | A8MVW5.1 |
| UniProt Secondary Accession: | A8MVW5,Q6UXI0, B3KTT4, B4DPJ1, B9EG93, E9PDV5 |
| UniProt Related Accession: | A8MVW5 |
| Molecular Weight: | 54,115 Da |
| NCBI Full Name: | HEPACAM family member 2 |
| NCBI Synonym Full Names: | HEPACAM family member 2 |
| NCBI Official Symbol: | HEPACAM2 |
| NCBI Official Synonym Symbols: | MIKI |
| NCBI Protein Information: | HEPACAM family member 2 |
| UniProt Protein Name: | HEPACAM family member 2 |
| UniProt Synonym Protein Names: | Mitotic kinetics regulator |
| Protein Family: | HEPACAM family |
| UniProt Gene Name: | HEPACAM2 |
| UniProt Entry Name: | HECA2_HUMAN |
