Description
| 抗体名: | HCRTR1 Antibody |
| 抗体コード: | PACO04037 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IF |
| 推奨される希釈: | IF:1:200-1:1000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human Orexin R-1. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | HCRTR1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1R; Hypocretin receptor type 1 |
| UniProt Protein Function: | HCRTR1: Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p33 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; neuropeptide receptor activity; orexin receptor activity; peptide binding Biological Process: cellular response to hormone stimulus; regulation of circadian sleep/wake cycle, sleep; synaptic transmission |
| NCBI Summary: | The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009] |
| UniProt Code: | O43613 |
| NCBI GenInfo Identifier: | 205804177 |
| NCBI Gene ID: | 3061 |
| NCBI Accession: | O43613.2 |
| UniProt Secondary Accession: | O43613,Q9HBV6, A8K3A6, |
| UniProt Related Accession: | O43613 |
| Molecular Weight: | 47,536 Da |
| NCBI Full Name: | Orexin receptor type 1 |
| NCBI Synonym Full Names: | hypocretin receptor 1 |
| NCBI Official Symbol: | HCRTR1 |
| NCBI Official Synonym Symbols: | OX1R |
| NCBI Protein Information: | orexin receptor type 1 |
| UniProt Protein Name: | Orexin receptor type 1 |
| UniProt Synonym Protein Names: | Hypocretin receptor type 1 |
| Protein Family: | Orexin receptor |
| UniProt Gene Name: | HCRTR1 |
| UniProt Entry Name: | OX1R_HUMAN |
