Description
| 抗体名: | GTF2B Antibody, FITC conjugated (PACO27247) |
| 抗体コード: | PACO27247 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Transcription initiation factor IIB protein (1-316AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II. |
| シノニム: | Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II), GTF2B, TF2B TFIIB |
| UniProt Protein Function: | GTF2B: General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II. Associates with TFIID-IIA (DA complex) to form TFIID-IIA- IIB (DAB-complex) which is then recognized by polymerase II. Interacts with the transcription elongation factor TCEA2. Interacts with HIV-1 Vpr. Interacts with GPBP1. Interacts with Epstein-Barr virus EBNA2. Belongs to the TFIIB family. |
| UniProt Protein Details: | Protein type:Acetyltransferase; Nuclear receptor co-regulator; Transcription factor Chromosomal Location of Human Ortholog: 1p22-p21 Cellular Component: nucleolus; nucleoplasm; nucleus Molecular Function:protein binding; thyroid hormone receptor binding; transcription factor binding Biological Process: RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q00403 |
| NCBI GenInfo Identifier: | 135629 |
| NCBI Gene ID: | 2959 |
| NCBI Accession: | Q00403.1 |
| UniProt Secondary Accession: | Q00403,Q5JS30, A8K1A7, |
| UniProt Related Accession: | Q00403 |
| Molecular Weight: | 34,833 Da |
| NCBI Full Name: | Transcription initiation factor IIB |
| NCBI Synonym Full Names: | general transcription factor IIB |
| NCBI Official Symbol: | GTF2B |
| NCBI Official Synonym Symbols: | TF2B; TFIIB |
| NCBI Protein Information: | transcription initiation factor IIB |
| UniProt Protein Name: | Transcription initiation factor IIB |
| UniProt Synonym Protein Names: | General transcription factor TFIIB; S300-II |
| Protein Family: | Transcription initiation factor |
| UniProt Gene Name: | GTF2B |
| UniProt Entry Name: | TF2B_HUMAN |
