| UniProt Protein Function: | GPRC5B: Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family.Protein type: GPCR, family 3; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCRChromosomal Location of Human Ortholog: 16p12Cellular Component: cell surface; extracellular space; intracellular membrane-bound organelle; nucleolus; nucleusMolecular Function: G-protein-coupled receptor binding; protein kinase activator activity; protein kinase bindingBiological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of inflammatory response; positive regulation of neuron differentiation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] |
| UniProt Code: | Q9NZH0 |
| NCBI GenInfo Identifier: | 46396016 |
| NCBI Gene ID: | 51704 |
| NCBI Accession: | Q9NZH0.2 |
| UniProt Secondary Accession: | Q9NZH0,O75205, Q8NBZ8, D2DFB0 |
| UniProt Related Accession: | Q9NZH0 |
| Molecular Weight: | 44,933 Da |
| NCBI Full Name: | G-protein coupled receptor family C group 5 member B |
| NCBI Synonym Full Names: | G protein-coupled receptor class C group 5 member B |
| NCBI Official Symbol: | GPRC5B |
| NCBI Official Synonym Symbols: | RAIG2; RAIG-2 |
| NCBI Protein Information: | G-protein coupled receptor family C group 5 member B |
| UniProt Protein Name: | G-protein coupled receptor family C group 5 member B |
| UniProt Synonym Protein Names: | A-69G12.1; Retinoic acid-induced gene 2 protein; RAIG-2 |
| Protein Family: | G-protein coupled receptor family |
| UniProt Gene Name: | GPRC5B |
| UniProt Entry Name: | GPC5B_HUMAN |
