Description
| 抗体名: | GPR75 Antibody, Biotin conjugated (PACO27172) |
| 抗体コード: | PACO27172 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Probable G-protein coupled receptor 75 protein (372-540AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. |
| シノニム: | Probable G-protein coupled receptor 75, GPR75 |
| UniProt Protein Function: | GPR75: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 2p16Cellular Component: integral to plasma membraneMolecular Function: C-C chemokine receptor activity; G-protein coupled receptor activityBiological Process: cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002] |
| UniProt Code: | O95800 |
| NCBI GenInfo Identifier: | 67460986 |
| NCBI Gene ID: | 10936 |
| NCBI Accession: | O95800.1 |
| UniProt Secondary Accession: | O95800,Q6NWR2, B2RC02 |
| UniProt Related Accession: | O95800 |
| Molecular Weight: | 59,359 Da |
| NCBI Full Name: | Probable G-protein coupled receptor 75 |
| NCBI Synonym Full Names: | G protein-coupled receptor 75 |
| NCBI Official Symbol: | GPR75 |
| NCBI Official Synonym Symbols: | GPRchr2; WI31133 |
| NCBI Protein Information: | probable G-protein coupled receptor 75 |
| UniProt Protein Name: | Probable G-protein coupled receptor 75 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Probable G-protein coupled receptor |
| UniProt Gene Name: | GPR75 |
| UniProt Entry Name: | GPR75_HUMAN |
