Description
| 抗体名: | GPR68 Antibody (PACO05412) |
| 抗体コード: | PACO05412 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IF |
| 推奨される希釈: | ELISA:1:5000, WB:1:500-1:2000, IF:1:200-1:1000 |
| 反応性: | Human, Mouse |
| 免疫原: | Synthesized peptide derived from the C-terminal region of human GPR68. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | GPR68; OGR1; Ovarian cancer G-protein coupled receptor 1; OGR-1; G-protein coupled receptor 68; GPR12A; Sphingosylphosphorylcholine receptor |
| UniProt Protein Function: | GPR68: Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Tumor suppressor; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR Chromosomal Location of Human Ortholog: 14q31 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; inflammatory response; negative regulation of monocyte differentiation |
| UniProt Code: | Q15743 |
| NCBI GenInfo Identifier: | 3024266 |
| NCBI Gene ID: | 8111 |
| NCBI Accession: | Q15743.1 |
| UniProt Secondary Accession: | Q15743,Q13334, Q4VBB4, Q6IX34, |
| UniProt Related Accession: | Q15743 |
| Molecular Weight: | 365 |
| NCBI Full Name: | Ovarian cancer G-protein coupled receptor 1 |
| NCBI Synonym Full Names: | G protein-coupled receptor 68 |
| NCBI Official Symbol: | GPR68 |
| NCBI Official Synonym Symbols: | OGR1; GPR12A |
| NCBI Protein Information: | ovarian cancer G-protein coupled receptor 1; G-protein coupled receptor 68; sphingosylphosphorylcholine receptor; ovarian cancer G protein-coupled receptor, 1 |
| UniProt Protein Name: | Ovarian cancer G-protein coupled receptor 1 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 68; GPR12A; Sphingosylphosphorylcholine receptor |
| Protein Family: | Ovarian cancer G-protein coupled receptor |
| UniProt Gene Name: | GPR68 |
| UniProt Entry Name: | OGR1_HUMAN |
