Description
| 抗体名: | GPR37 Antibody, FITC conjugated (PACO63929) |
| 抗体コード: | PACO63929 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Peptide sequence from Human Prosaposin receptor GPR37 protein (114-133AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade. |
| シノニム: | Prosaposin receptor GPR37 (Endothelin B receptor-like protein 1) (ETBR-LP-1) (G-protein coupled receptor 37) (Parkin-associated endothelin receptor-like receptor) (PAELR), GPR37 |
| UniProt Protein Function: | GPR37: Orphan receptor. May have a unique functional role in the central nervous system. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1 Chromosomal Location of Human Ortholog: 7q31 Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane; plasma membrane; ubiquitin ligase complex; receptor complex Molecular Function:G-protein coupled receptor activity; protein binding; ubiquitin protein ligase binding; heat shock protein binding; peptide receptor activity, G-protein coupled; Hsp70 protein binding; peptide binding Biological Process: positive regulation of dopamine metabolic process; G-protein coupled receptor protein signaling pathway; positive regulation of MAPKKK cascade; dopamine biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; locomotion during locomotory behavior |
| NCBI Summary: | This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012] |
| UniProt Code: | O15354 |
| NCBI GenInfo Identifier: | 4885323 |
| NCBI Gene ID: | 2861 |
| NCBI Accession: | NP_005293.1 |
| UniProt Secondary Accession: | O15354,O00348, O14768, Q8TD39, |
| UniProt Related Accession: | O15354 |
| Molecular Weight: | 67,114 Da |
| NCBI Full Name: | probable G-protein coupled receptor 37 |
| NCBI Synonym Full Names: | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| NCBI Official Symbol: | GPR37 |
| NCBI Official Synonym Symbols: | PAELR; EDNRBL; hET(B)R-LP |
| NCBI Protein Information: | probable G-protein coupled receptor 37; ETBR-LP-1; endothelin B receptor-like protein 1; Parkin-associated endothelin receptor-like receptor |
| UniProt Protein Name: | Probable G-protein coupled receptor 37 |
| UniProt Synonym Protein Names: | Endothelin B receptor-like protein 1; ETBR-LP-1; Parkin-associated endothelin receptor-like receptor |
| Protein Family: | Prosaposin receptor |
| UniProt Gene Name: | GPR37 |
| UniProt Entry Name: | GPR37_HUMAN |
