Description
| 抗体名: | GNB5 Antibody, FITC conjugated (PACO27075) |
| 抗体コード: | PACO27075 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Guanine nucleotide-binding protein subunit beta-5 protein (1-353AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The β and γ chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
| シノニム: | Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin β chain 5), GNB5 |
| UniProt Protein Function: | G-beta 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:G protein, heterotrimeric beta Chromosomal Location of Human Ortholog: 15q21.2 Cellular Component: plasma membrane; nucleus Molecular Function:GTPase activity; G-protein gamma-subunit binding; signal transducer activity; protein binding; chaperone binding Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; metabolic process; signal transduction |
| NCBI Summary: | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14775 |
| NCBI GenInfo Identifier: | 38258891 |
| NCBI Gene ID: | 10681 |
| NCBI Accession: | O14775.2 |
| UniProt Secondary Accession: | O14775,Q9HAU9, Q9UFT3, B2RBR5, |
| UniProt Related Accession: | O14775 |
| Molecular Weight: | 395 |
| NCBI Full Name: | Guanine nucleotide-binding protein subunit beta-5 |
| NCBI Synonym Full Names: | guanine nucleotide binding protein (G protein), beta 5 |
| NCBI Official Symbol: | GNB5 |
| NCBI Official Synonym Symbols: | GB5 |
| NCBI Protein Information: | guanine nucleotide-binding protein subunit beta-5; gbeta5; transducin beta chain 5; G protein, beta-5 subunit; G protein, beta subunit 5L; guanine nucleotide-binding protein, beta subunit 5L |
| UniProt Protein Name: | Guanine nucleotide-binding protein subunit beta-5 |
| UniProt Synonym Protein Names: | Gbeta5; Transducin beta chain 5 |
| Protein Family: | Guanine nucleotide-binding protein |
| UniProt Gene Name: | GNB5 |
| UniProt Entry Name: | GBB5_HUMAN |
