Description
| 抗体名: | GJC1 Antibody (PACO43013) |
| 抗体コード: | PACO43013 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Gap junction gamma-1 protein (247-396AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: Gap junction gamma-1 protein antibody at 6µg/ml + 293T whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO43013 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43013 at dilution of 1:100. |
| バックグラウンド: | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| シノニム: | Gap junction gamma-1 protein (Connexin-45) (Cx45) (Gap junction alpha-7 protein), GJC1, GJA7 |
| UniProt Protein Function: | GJC1: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 17q21.31 Cellular Component: connexon complex; endoplasmic reticulum membrane; plasma membrane; gap junction; integral to membrane Molecular Function:ion channel activity; gap junction channel activity Biological Process: cardiac muscle development; intercellular junction assembly; synaptic transmission; gap junction assembly; visual perception; muscle contraction; transport; vasculogenesis; cell development |
| NCBI Summary: | This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P36383 |
| NCBI GenInfo Identifier: | 226693517 |
| NCBI Gene ID: | 10052 |
| NCBI Accession: | P36383.2 |
| UniProt Secondary Accession: | P36383,Q4VAY0, B3KW68, |
| UniProt Related Accession: | P36383 |
| Molecular Weight: | 45,470 Da |
| NCBI Full Name: | Gap junction gamma-1 protein |
| NCBI Synonym Full Names: | gap junction protein, gamma 1, 45kDa |
| NCBI Official Symbol: | GJC1 |
| NCBI Official Synonym Symbols: | CX45; GJA7 |
| NCBI Protein Information: | gap junction gamma-1 protein; connexin 45; connexin-45; gap junction alpha-7 protein |
| UniProt Protein Name: | Gap junction gamma-1 protein |
| UniProt Synonym Protein Names: | Connexin-45; Cx45; Gap junction alpha-7 protein |
| Protein Family: | Gap junction gamma-1 protein |
| UniProt Gene Name: | GJC1 |
| UniProt Entry Name: | CXG1_HUMAN |
