Description
| 抗体名: | GGPS1 Antibody, HRP conjugated (PACO26958) |
| 抗体コード: | PACO26958 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Geranylgeranyl pyrophosphate synthase protein (1-300AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | HRP |
| バックグラウンド: | Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. |
| シノニム: | Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10), GGPS1 |
| UniProt Protein Function: | GGPS1: Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. Belongs to the FPP/GGPP synthase family. |
| UniProt Protein Details: | Protein type:Transferase; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; EC 2.5.1.10; EC 2.5.1.29; Motility/polarity/chemotaxis; EC 2.5.1.1 Chromosomal Location of Human Ortholog: 1q43 Cellular Component: cytosol Molecular Function:geranyltranstransferase activity; dimethylallyltranstransferase activity; farnesyltranstransferase activity; metal ion binding Biological Process: isoprenoid metabolic process; geranylgeranyl diphosphate biosynthetic process; geranyl diphosphate biosynthetic process; farnesyl diphosphate biosynthetic process; cholesterol biosynthetic process |
| NCBI Summary: | This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010] |
| UniProt Code: | O95749 |
| NCBI GenInfo Identifier: | 6831549 |
| NCBI Gene ID: | 9453 |
| NCBI Accession: | O95749.1 |
| UniProt Related Accession: | O95749 |
| Molecular Weight: | 28kDa; 34kDa |
| NCBI Full Name: | Geranylgeranyl pyrophosphate synthase |
| NCBI Synonym Full Names: | geranylgeranyl diphosphate synthase 1 |
| NCBI Official Symbol: | GGPS1 |
| NCBI Official Synonym Symbols: | GGPPS; GGPPS1 |
| NCBI Protein Information: | geranylgeranyl pyrophosphate synthase |
| UniProt Protein Name: | Geranylgeranyl pyrophosphate synthase |
| UniProt Synonym Protein Names: | (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase (EC:2.5.1.1); Farnesyl diphosphate synthase; Farnesyltranstransferase (EC:2.5.1.29); Geranylgeranyl diphosphate synthase; Geranyltranstransferase (EC:2.5.1.10) |
| UniProt Gene Name: | GGPS1 |
| UniProt Entry Name: | GGPPS_HUMAN |
