GenieFluor Violet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody [D7] (AGEL3345)

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SKU:
AGEL3345
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
D7
Conjugation:
AFViolet 450
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GenieFluor Violet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody [D7]

The GenieFluor Violet 450 Anti-Mouse LY6A/E SCA-1 Antibody (D7) is a powerful tool for researchers interested in studying LY6A/E SCA-1, a cell surface marker associated with stem cells and immune regulation. This antibody, generated specifically for use in mouse samples, is designed to detect and target the LY6A/E SCA-1 protein in various experimental applications, including flow cytometry, immunofluorescence, and immunohistochemistry.LY6A/E SCA-1, also known as Stem Cell Antigen-1, is a multifunctional marker expressed on various cell types, including hematopoietic stem cells, endothelial cells, and activated T cells. Its role in stemness and immune regulation makes it a key molecule in research related to stem cell biology, immunology, and cancer.

By using this antibody, researchers can investigate the expression and localization of LY6A/E SCA-1 in different tissues and cell populations, providing insights into its function and potential therapeutic implications.The GenieFluor Violet 450 Anti-Mouse LY6A/E SCA-1 Antibody (D7) offers high specificity and sensitivity, allowing for accurate and reliable detection of LY6A/E SCA-1 in complex biological samples. Its versatility and compatibility with various experimental techniques make it an essential reagent for scientists studying stem cell biology, immune responses, and disease pathology in mouse models.

Product Title:GenieFluor Violet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody [D7]
SKU:AGEL3345
Size:25µg, 100µg
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
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