Description
| 抗体名: | GEM Antibody (PACO43459) |
| 抗体コード: | PACO43459 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human GTP-binding protein GEM protein (1-150AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO43459 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43459 at dilution of 1:100. |
| バックグラウンド: | Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. |
| シノニム: | GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR), GEM, KIR |
| UniProt Protein Function: | GEM: Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Belongs to the small GTPase superfamily. RGK family. |
| UniProt Protein Details: | Protein type:G protein, monomeric; G protein; G protein, monomeric, RGK Chromosomal Location of Human Ortholog: 8q13-q21 Cellular Component: internal side of plasma membrane; midbody; spindle midzone; nucleus Molecular Function:calmodulin binding; GTPase activity; protein binding; GDP binding; GTP binding; magnesium ion binding Biological Process: mitosis; cell surface receptor linked signal transduction; metabolic process; small GTPase mediated signal transduction; metaphase plate congression; immune response; signal transduction; chromosome organization and biogenesis |
| NCBI Summary: | The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P55040 |
| NCBI GenInfo Identifier: | 1707896 |
| NCBI Gene ID: | 2669 |
| NCBI Accession: | P55040.1 |
| UniProt Secondary Accession: | P55040,B2RA31, |
| UniProt Related Accession: | P55040 |
| Molecular Weight: | 296 |
| NCBI Full Name: | GTP-binding protein GEM |
| NCBI Synonym Full Names: | GTP binding protein overexpressed in skeletal muscle |
| NCBI Official Symbol: | GEM |
| NCBI Official Synonym Symbols: | KIR |
| NCBI Protein Information: | GTP-binding protein GEM; RAS-like protein KIR; kinase-inducible Ras-like protein; GTP-binding mitogen-induced T-cell protein; GTP-binding protein overexpressed in skeletal muscle |
| UniProt Protein Name: | GTP-binding protein GEM |
| UniProt Synonym Protein Names: | GTP-binding mitogen-induced T-cell protein; RAS-like protein KIR |
| Protein Family: | Geminin |
| UniProt Gene Name: | GEM |
| UniProt Entry Name: | GEM_HUMAN |
