Description
| 抗体名: | GDI2 Antibody, HRP conjugated (PACO26946) |
| 抗体コード: | PACO26946 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Rab GDP dissociation inhibitor β protein (1-445AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | HRP |
| バックグラウンド: | Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. |
| シノニム: | Rab GDP dissociation inhibitor β (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2), GDI2, RABGDIB |
| UniProt Protein Function: | GDI2: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Belongs to the Rab GDI family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:G protein regulator, misc.; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 10p15 Cellular Component: cytoplasm; cytosol; focal adhesion; vesicle Molecular Function:protein binding Biological Process: regulation of small GTPase mediated signal transduction; signal transduction |
| NCBI Summary: | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P50395 |
| NCBI GenInfo Identifier: | 13638228 |
| NCBI Gene ID: | 2665 |
| NCBI Accession: | P50395.2 |
| UniProt Secondary Accession: | P50395,O43928, Q5SX88, Q9UQM6, |
| UniProt Related Accession: | P50395 |
| Molecular Weight: | 45,619 Da |
| NCBI Full Name: | Rab GDP dissociation inhibitor beta |
| NCBI Synonym Full Names: | GDP dissociation inhibitor 2 |
| NCBI Official Symbol: | GDI2 |
| NCBI Official Synonym Symbols: | RABGDIB; HEL-S-46e |
| NCBI Protein Information: | rab GDP dissociation inhibitor beta |
| UniProt Protein Name: | Rab GDP dissociation inhibitor beta |
| UniProt Synonym Protein Names: | Guanosine diphosphate dissociation inhibitor 2; GDI-2 |
| Protein Family: | Guanosine nucleotide diphosphate dissociation inhibitor |
| UniProt Gene Name: | GDI2 |
| UniProt Entry Name: | GDIB_HUMAN |
