| UniProt Protein Function: | GCM1: Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 6p12.1 Cellular Component: transcription factor complex; nucleus Molecular Function:protein binding; DNA binding; zinc ion binding; histone deacetylase binding; transcription factor binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; positive regulation of syncytium formation by plasma membrane fusion; anatomical structure morphogenesis; regulation of transcription, DNA-dependent; astrocyte fate commitment; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NP62 |
| NCBI GenInfo Identifier: | 33516903 |
| NCBI Gene ID: | 8521 |
| NCBI Accession: | Q9NP62.1 |
| UniProt Secondary Accession: | Q9NP62,Q4VAQ7, Q5T0X0, Q99468, Q9P1X3, |
| UniProt Related Accession: | Q9NP62 |
| Molecular Weight: | 49,268 Da |
| NCBI Full Name: | Chorion-specific transcription factor GCMa |
| NCBI Synonym Full Names: | glial cells missing homolog 1 (Drosophila) |
| NCBI Official Symbol: | GCM1 |
| NCBI Official Synonym Symbols: | GCMA; hGCMa |
| NCBI Protein Information: | chorion-specific transcription factor GCMa; GCM motif protein 1 |
| UniProt Protein Name: | Chorion-specific transcription factor GCMa |
| UniProt Synonym Protein Names: | GCM motif protein 1; Glial cells missing homolog 1 |
| Protein Family: | Chorion-specific transcription factor |
| UniProt Gene Name: | GCM1 |
| UniProt Entry Name: | GCM1_HUMAN |
