Description
| 抗体名: | GBA3 Antibody (PACO09423) |
| 抗体コード: | PACO09423 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Human GBA3 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | glucosidase, beta, acid, 3 (cytosolic);GBA3;CBGL1;GLUC;KLrP;MGC104276;MGC126878 ; |
| UniProt Protein Function: | GBA3: Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - starch and sucrose; Hydrolase; EC 3.2.1.21; Other Amino Acids Metabolism - cyanoamino acid Chromosomal Location of Human Ortholog: 4p15.2 Cellular Component: cytosol Molecular Function:beta-galactosidase activity; beta-glucosidase activity; glucosylceramidase activity; glycosylceramidase activity Biological Process: glycoside catabolic process; glycosphingolipid metabolic process; glycosylceramide catabolic process |
| NCBI Summary: | The protein encoded by this gene is an enzyme that can hydrolyze several types of glycosides. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals, as represented by the reference genome allele, contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2013] |
| UniProt Code: | Q9H227 |
| NCBI GenInfo Identifier: | 77416427 |
| NCBI Gene ID: | 57733 |
| NCBI Accession: | Q9H227.2 |
| UniProt Secondary Accession: | Q9H227,Q32LY7, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4 Q9H4C6, |
| UniProt Related Accession: | Q9H227 |
| Molecular Weight: | 18,265 Da |
| NCBI Full Name: | Cytosolic beta-glucosidase |
| NCBI Synonym Full Names: | glucosylceramidase beta 3 (gene/pseudogene) |
| NCBI Official Symbol: | GBA3 |
| NCBI Official Synonym Symbols: | CBG; GLUC; KLRP; CBGL1 |
| NCBI Protein Information: | cytosolic beta-glucosidase |
| UniProt Protein Name: | Cytosolic beta-glucosidase |
| UniProt Synonym Protein Names: | Cytosolic beta-glucosidase-like protein 1 |
| Protein Family: | Cytosolic beta-glucosidase |
| UniProt Gene Name: | GBA3 |
| UniProt Entry Name: | GBA3_HUMAN |
