Description
| 抗体名: | GAS2 Antibody, Biotin conjugated (PACO26928) |
| 抗体コード: | PACO26928 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Growth arrest-specific protein 2 protein (1-141AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process. |
| シノニム: | Growth arrest-specific protein 2 (GAS-2), GAS2 |
| UniProt Protein Function: | GAS2: May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process. Belongs to the GAS2 family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Apoptosis Chromosomal Location of Human Ortholog: 11p14.3 Cellular Component: membrane; actin filament; cytosol Biological Process: regulation of cell shape; apoptosis; cell cycle arrest; cell structure disassembly during apoptosis |
| NCBI Summary: | The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009] |
| UniProt Code: | O43903 |
| NCBI GenInfo Identifier: | 3913719 |
| NCBI Gene ID: | 2620 |
| NCBI Accession: | O43903.1 |
| UniProt Secondary Accession: | O43903,Q6ICV8, Q7Z3X8, B2R9C8, D3DQZ0, |
| UniProt Related Accession: | O43903 |
| Molecular Weight: | 313 |
| NCBI Full Name: | Growth arrest-specific protein 2 |
| NCBI Synonym Full Names: | growth arrest-specific 2 |
| NCBI Official Symbol: | GAS2 |
| NCBI Protein Information: | growth arrest-specific protein 2; GAS-2 |
| UniProt Protein Name: | Growth arrest-specific protein 2 |
| Protein Family: | GAS2-like protein |
| UniProt Gene Name: | GAS2 |
| UniProt Entry Name: | GAS2_HUMAN |
