Description
| 抗体名: | GADD45G Antibody (PACO45291) |
| 抗体コード: | PACO45291 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| 反応性: | Human, Rat |
| 免疫原: | Recombinant Human Growth arrest and DNA damage-inducible protein GADD45 γ protein (1-159AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: GADD45G antibody IgG at 5.39µg/ml + Rat heart tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 17 kDa. Observed band size: 17 kDa.. |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO45291 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO45291 at dilution of 1:100. |
| バックグラウンド: | Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. |
| シノニム: | Growth arrest and DNA damage-inducible protein GADD45 γ (Cytokine-responsive protein CR6) (DNA damage-inducible transcript 2 protein) (DDIT-2), GADD45G, CR6 DDIT2 |
| UniProt Protein Function: | GADD45G: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. Belongs to the GADD45 family. |
| UniProt Protein Details: | Protein type:Apoptosis; DNA repair, damage; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 9q22.2 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding Biological Process: activation of MAPKKK activity; positive regulation of apoptosis; positive regulation of JNK cascade; regulation of cell cycle |
| NCBI Summary: | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95257 |
| NCBI GenInfo Identifier: | 6919892 |
| NCBI Gene ID: | 10912 |
| NCBI Accession: | O95257.1 |
| UniProt Secondary Accession: | O95257,Q5VZ87, Q9C076, |
| UniProt Related Accession: | O95257 |
| Molecular Weight: | 17kDa |
| NCBI Full Name: | Growth arrest and DNA damage-inducible protein GADD45 gamma |
| NCBI Synonym Full Names: | growth arrest and DNA damage inducible gamma |
| NCBI Official Symbol: | GADD45G |
| NCBI Official Synonym Symbols: | CR6; DDIT2; GRP17; GADD45gamma |
| NCBI Protein Information: | growth arrest and DNA damage-inducible protein GADD45 gamma |
| UniProt Protein Name: | Growth arrest and DNA damage-inducible protein GADD45 gamma |
| UniProt Synonym Protein Names: | Cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein; DDIT-2 |
| Protein Family: | Growth arrest and DNA damage-inducible protein |
| UniProt Gene Name: | GADD45G |
| Antibodies | ELISA Kits |
| Anti-GADD45G Antibody (CAB10286) | Human Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G) ELISA Kit |
| GADD45G Antibody (PACO00832) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
