Description
| 抗体名: | FUT8 Antibody (PACO09363) |
| 抗体コード: | PACO09363 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human FUT8 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | fucosyltransferase 8 (α (1,6) fucosyltransferase);FUT8;MGC26465 ; |
| UniProt Protein Function: | FUT8: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.4.1.68; Glycan Metabolism - N-glycan biosynthesis; Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral; Motility/polarity/chemotaxis; Transferase Chromosomal Location of Human Ortholog: 14q23.3 Cellular Component: cytosol; Golgi membrane; membrane Molecular Function:glycoprotein 6-alpha-L-fucosyltransferase activity Biological Process: GDP-L-fucose metabolic process; N-glycan processing; oligosaccharide biosynthetic process; protein amino acid N-linked glycosylation; protein amino acid N-linked glycosylation via asparagine |
| NCBI Summary: | This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011] |
| UniProt Code: | Q9BYC5 |
| NCBI GenInfo Identifier: | 20138326 |
| NCBI Gene ID: | 2530 |
| NCBI Accession: | Q9BYC5.2 |
| UniProt Secondary Accession: | Q9BYC5,O00235, Q8IUA5, Q9BYC6, Q9P2U5, Q9P2U6, B4DFS7 G3V5N0, |
| UniProt Related Accession: | Q9BYC5 |
| Molecular Weight: | Calculated MW: 19kDa/35kDa/47kDa/66kDaObserved MW: 75kDa |
| NCBI Full Name: | Alpha-(1,6)-fucosyltransferase |
| NCBI Synonym Full Names: | fucosyltransferase 8 |
| NCBI Official Symbol: | FUT8 |
| NCBI Protein Information: | alpha-(1,6)-fucosyltransferase |
| UniProt Protein Name: | Alpha-(1,6)-fucosyltransferase |
| UniProt Synonym Protein Names: | Fucosyltransferase 8; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase |
| Protein Family: | Probable fucosyltransferase |
| UniProt Gene Name: | FUT8 |
