Description
| 抗体名: | FRS2 Antibody (PACO09347) |
| 抗体コード: | PACO09347 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human FRS2 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | fibroblast growth factor receptor substrate 2;FRS2;FRS2A;FRS2alpha;SNT;SNT-1;SNT1 ; |
| UniProt Protein Function: | FRS2: an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 12q15 Cellular Component: endosome; integral to plasma membrane; membrane; plasma membrane Molecular Function:1-phosphatidylinositol-3-kinase activity; fibroblast growth factor receptor binding; neurotrophin TRKA receptor binding; phosphatase activator activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; Ras guanyl-nucleotide exchange factor activity; transmembrane receptor protein tyrosine kinase adaptor protein activity Biological Process: activation of MAPKK activity; fibroblast growth factor receptor signaling pathway; G-protein coupled receptor protein signaling pathway; MAPKKK cascade; phosphoinositide-mediated signaling; regulation of phosphoinositide 3-kinase cascade; transmembrane receptor protein tyrosine phosphatase signaling pathway |
| UniProt Code: | Q8WU20 |
| NCBI GenInfo Identifier: | 209572769 |
| NCBI Gene ID: | 10818 |
| NCBI Accession: | Q8WU20.4 |
| UniProt Secondary Accession: | Q8WU20,O43558, Q7LDQ6, B0LPF2, B2R684, |
| UniProt Related Accession: | Q8WU20 |
| Molecular Weight: | 57,029 Da |
| NCBI Full Name: | Fibroblast growth factor receptor substrate 2 |
| NCBI Synonym Full Names: | fibroblast growth factor receptor substrate 2 |
| NCBI Official Symbol: | FRS2 |
| NCBI Official Synonym Symbols: | SNT; SNT1; FRS1A; FRS2A; SNT-1; FRS2alpha |
| NCBI Protein Information: | fibroblast growth factor receptor substrate 2 |
| UniProt Protein Name: | Fibroblast growth factor receptor substrate 2 |
| UniProt Synonym Protein Names: | FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1 |
| Protein Family: | Fibroblast growth factor receptor substrate |
| UniProt Gene Name: | FRS2 |
| UniProt Entry Name: | FRS2_HUMAN |