| UniProt Protein Function: | FCRL5: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities derived from Burkitt lymphoma. Duplication dup(1)(q21q32). 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell surface Chromosomal Location of Human Ortholog: 1q21 Cellular Component: receptor complex |
| NCBI Summary: | This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010] |
| UniProt Code: | Q96RD9 |
| NCBI GenInfo Identifier: | 296439341 |
| NCBI Gene ID: | 83416 |
| NCBI Accession: | Q96RD9.3 |
| UniProt Secondary Accession: | Q96RD9,Q495Q2, Q495Q4, Q5VYK9, Q6UY46, A0N0M2, B7WNT9 B7WP94, |
| UniProt Related Accession: | Q96RD9 |
| Molecular Weight: | |
| NCBI Full Name: | Fc receptor-like protein 5 |
| NCBI Synonym Full Names: | Fc receptor like 5 |
| NCBI Official Symbol: | FCRL5 |
| NCBI Official Synonym Symbols: | CD307; FCRH5; IRTA2; BXMAS1; CD307e; PRO820 |
| NCBI Protein Information: | Fc receptor-like protein 5 |
| UniProt Protein Name: | Fc receptor-like protein 5 |
| UniProt Synonym Protein Names: | BXMAS1; Fc receptor homolog 5; FcRH5; Immune receptor translocation-associated protein 2; CD_antigen: CD307e |
| Protein Family: | Fc receptor-like protein |
| UniProt Gene Name: | FCRL5 |
| UniProt Entry Name: | FCRL5_HUMAN |
