| UniProt Protein Function: | FARSLB: a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ligase; EC 6.1.1.20; Translation Chromosomal Location of Human Ortholog: 2q36.1 Cellular Component: membrane; cytoplasm; cytosol Molecular Function:RNA binding; phenylalanine-tRNA ligase activity; magnesium ion binding; ATP binding Biological Process: tRNA aminoacylation for protein translation; translation; phenylalanyl-tRNA aminoacylation; gene expression |
| NCBI Summary: | This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| UniProt Code: | Q9NSD9 |
| NCBI GenInfo Identifier: | 296452943 |
| NCBI Gene ID: | 10056 |
| NCBI Accession: | Q9NSD9.3 |
| UniProt Related Accession: | Q9NSD9 |
| Molecular Weight: | |
| NCBI Full Name: | Phenylalanine--tRNA ligase beta subunit |
| NCBI Synonym Full Names: | phenylalanyl-tRNA synthetase subunit beta |
| NCBI Official Symbol: | FARSB |
| NCBI Official Synonym Symbols: | FRSB; PheHB; PheRS; FARSLB; RILDBC; HSPC173; NEDBLLA |
| NCBI Protein Information: | phenylalanine--tRNA ligase beta subunit |
| UniProt Protein Name: | Phenylalanine--tRNA ligase beta subunit |
| UniProt Synonym Protein Names: | Phenylalanyl-tRNA synthetase beta subunit; PheRS |
| UniProt Gene Name: | FARSB |
| UniProt Entry Name: | SYFB_HUMAN |
