Description
| 抗体名: | FAIM Antibody (PACO42262) |
| 抗体コード: | PACO42262 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| 反応性: | Human, Rat |
| 免疫原: | Recombinant Human Fas apoptotic inhibitory molecule 1 protein (1-179AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: FAIM antibody at 2µg/ml. Lane 1: 293T whole cell lysate. Lane 2: Rat gonad tissue. Lane 3: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 21, 25, 23 kDa. Observed band size: 21 kDa. |
 | Immunofluorescence staining of HepG2 cells with PACO42262 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO42262 at dilution of 1:100. |
| バックグラウンド: | Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. |
| シノニム: | Fas apoptotic inhibitory molecule 1, FAIM, FAIM1 |
| UniProt Protein Function: | FAIM: Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Belongs to the FAIM1 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 3q22.3 Cellular Component: cytoplasm Biological Process: apoptosis; negative regulation of apoptosis |
| NCBI Summary: | The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] |
| UniProt Code: | Q9NVQ4 |
| NCBI GenInfo Identifier: | 38503210 |
| NCBI Gene ID: | 55179 |
| NCBI Accession: | Q9NVQ4.1 |
| UniProt Related Accession: | Q9NVQ4 |
| Molecular Weight: | 20kDa |
| NCBI Full Name: | Fas apoptotic inhibitory molecule 1 |
| NCBI Synonym Full Names: | Fas apoptotic inhibitory molecule |
| NCBI Official Symbol: | FAIM |
| NCBI Official Synonym Symbols: | FAIM1 |
| NCBI Protein Information: | fas apoptotic inhibitory molecule 1 |
| UniProt Protein Name: | Fas apoptotic inhibitory molecule 1 |
| Protein Family: | Fas apoptotic inhibitory molecule |
| UniProt Gene Name: | FAIM |
| UniProt Entry Name: | FAIM1_HUMAN |
