Description
| 抗体名: | EXD2 Antibody, FITC conjugated (PACO47084) |
| 抗体コード: | PACO47084 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Exonuclease 3'-5' domain-containing protein 2 protein (137-245AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. |
| シノニム: | Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2), EXD2, C14orf114 EXDL2 |
| UniProt Protein Function: | EXDL2: Belongs to the EXD2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 14q24.1Cellular Component: cytoplasm; nucleusMolecular Function: nucleic acid binding; 3'-5' exonuclease activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NVH0 |
| NCBI GenInfo Identifier: | 410516875 |
| NCBI Gene ID: | 55218 |
| NCBI Accession: | Q9NVH0.2 |
| UniProt Secondary Accession: | Q9NVH0 |
| UniProt Related Accession: | Q9NVH0 |
| Molecular Weight: | 70 kDa |
| NCBI Full Name: | Exonuclease 3'-5' domain-containing protein 2 |
| NCBI Synonym Full Names: | exonuclease 3'-5' domain containing 2 |
| NCBI Official Symbol: | EXD2 |
| NCBI Official Synonym Symbols: | EXDL2; C14orf114 |
| NCBI Protein Information: | exonuclease 3'-5' domain-containing protein 2 |
| UniProt Protein Name: | Exonuclease 3'-5' domain-containing protein 2 |
| UniProt Synonym Protein Names: | Exonuclease 3'-5' domain-like-containing protein 2 |
| Protein Family: | Exonuclease 3'-5' domain-containing protein |
| UniProt Gene Name: | EXD2 |
| UniProt Entry Name: | EXD2_HUMAN |
