Description
| 抗体名: | ERCC6L Antibody (PACO09132) |
| 抗体コード: | PACO09132 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human ERCC6L |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | excision repair cross-complementing rodent repair deficiency, complementation group 6-like;ERCC6L;FLJ20105;MGC131695;PICH ; |
| UniProt Protein Function: | PICH: DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. Interacts with PLK1, which phosphorylates it. Both proteins are mutually dependent on each other for correct subcellular localization. Belongs to the SNF2/RAD54 helicase family. |
| UniProt Protein Details: | Protein type:Helicase; EC 3.6.4.12 Chromosomal Location of Human Ortholog: Xq13.1 Cellular Component: nucleoplasm; centrosome; membrane; cytoplasm; plasma membrane; cytosol Molecular Function:protein binding; DNA binding; helicase activity; ATP binding Biological Process: mitosis; metabolic process; cell division; mitotic cell cycle |
| UniProt Code: | Q2NKX8 |
| NCBI GenInfo Identifier: | 121948339 |
| NCBI Gene ID: | 54821 |
| NCBI Accession: | Q2NKX8.1 |
| UniProt Secondary Accession: | Q2NKX8,Q8NCI1, Q96H93, Q9NXQ8, |
| UniProt Related Accession: | Q2NKX8 |
| Molecular Weight: | 1250 |
| NCBI Full Name: | DNA excision repair protein ERCC-6-like |
| NCBI Synonym Full Names: | excision repair cross-complementation group 6-like |
| NCBI Official Symbol: | ERCC6L |
| NCBI Official Synonym Symbols: | PICH; RAD26L |
| NCBI Protein Information: | DNA excision repair protein ERCC-6-like; tumor antigen BJ-HCC-15; SNF2/RAD54 family protein; ATP-dependent helicase ERCC6-like; excision repair protein ERCC6-like; Plk1-interacting checkpoint helicase; excision repair cross-complementing rodent repair def |
| UniProt Protein Name: | DNA excision repair protein ERCC-6-like |
| UniProt Synonym Protein Names: | ATP-dependent helicase ERCC6-like; PLK1-interacting checkpoint helicase; Tumor antigen BJ-HCC-15 |
| UniProt Gene Name: | ERCC6L |
| UniProt Entry Name: | ERC6L_HUMAN |
