Description
| 抗体名: | ERCC4 Antibody (PACO52678) |
| 抗体コード: | PACO52678 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human DNA repair endonuclease XPF protein (656-753AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO52678 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO52678 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO52678 at dilution of 1:100. |
| バックグラウンド: | Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. |
| シノニム: | DNA repair endonuclease XPF (EC 3.1) (DNA excision repair protein ERCC-4) (DNA repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein), ERCC4, ERCC11 XPF |
| UniProt Protein Function: | Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. |
| NCBI Summary: | The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009] |
| UniProt Code: | Q92889 |
| NCBI GenInfo Identifier: | 4885217 |
| NCBI Gene ID: | 2072 |
| NCBI Accession: | NP_005227.1 |
| UniProt Secondary Accession: | Q92889,O00140, Q8TD83, A5PKV6, A8K111, |
| UniProt Related Accession: | Q92889 |
| Molecular Weight: | 103 kDa |
| NCBI Full Name: | DNA repair endonuclease XPF |
| NCBI Synonym Full Names: | ERCC excision repair 4, endonuclease catalytic subunit |
| NCBI Official Symbol: | ERCC4 |
| NCBI Official Synonym Symbols: | XPF; RAD1; FANCQ; XFEPS; ERCC11 |
| NCBI Protein Information: | DNA repair endonuclease XPF |
| UniProt Protein Name: | DNA repair endonuclease XPF |
| UniProt Synonym Protein Names: | DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein |
| Protein Family: | Positive control factor |
| UniProt Gene Name: | ERCC4 |
| Antibodies | ELISA Kits |
| Anti-ERCC4 Antibody (CAB8119) | XPF Colorimetric Cell-Based ELISA Kit |
| ERCC4 Antibody (PACO06472) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
