Description
| Product Name: | Equine IFN g Recombinant Protein |
| Product Code: | RPPB0403 |
| Size: | 20µg |
| Species: | Equine |
| Target: | IFN g |
| Synonyms: | Interferon gamma, IFN-gamma, IFNG. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Lyophilized from a 0.2�m filtered concentrated solution in PBS, pH 7.4 and 5% trehalose. |
| Solubility: | It is recommended to reconstitute the lyophilized Interferon-gamma in sterile 18M-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized Interferon-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-gamma should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | QAAFFKEIEN LKEYFNASNP DVGDGGPLFL DILKNWKEDS DKKIIQSQIV SFYFKLFENL KDNQVIQKSM DTIKEDLFVK FFNSSTSKLE DFQKLIQIPV NDLKVQRKAI SELIKVMNDL SPKANLRKRK RSQNPFRGRR ALQ |
| Biological Activity: | The ED50 as determined by an anti-viral assay using human HeLa cells infected with encephalomyocarditis (EMC) virus is less than 10.0 ng/ml, corresponding to a specific activity of > 1.0 � 105 IU/mg. |
IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Recombinant Equine Interferon-gamma produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 143 amino acids and having a molecular mass of 16.7kDa.The IFN-gamma Equine is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| UniProt Code: | P42160 |
| NCBI GenInfo Identifier: | 1170561 |
| NCBI Gene ID: | 100034181 |
| NCBI Accession: | P42160.1 |
| UniProt Secondary Accession: | P42160,Q28387, |
| UniProt Related Accession: | P42160 |
| Molecular Weight: | 19,338 Da |
| NCBI Full Name: | Interferon gamma |
| NCBI Official Symbol: | IFNG�� |
| NCBI Protein Information: | interferon gamma |
| UniProt Protein Name: | Interferon gamma |
| Protein Family: | Interferon |
| UniProt Gene Name: | IFNG�� |
