| UniProt Protein Function: | ELOVL6: Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16:0 acyl-CoAs. Belongs to the ELO family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; EC 2.3.1.199Chromosomal Location of Human Ortholog: 4q25Cellular Component: endoplasmic reticulum; endoplasmic reticulum membraneMolecular Function: fatty acid elongase activity; protein bindingBiological Process: fatty acid elongation, saturated fatty acid; long-chain fatty acid biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9H5J4 |
| NCBI GenInfo Identifier: | 74733585 |
| NCBI Gene ID: | 79071 |
| NCBI Accession: | Q9H5J4.1 |
| UniProt Secondary Accession: | Q9H5J4,Q4W5L0, Q8NCD1 |
| UniProt Related Accession: | Q9H5J4 |
| Molecular Weight: | 31,376 Da |
| NCBI Full Name: | Elongation of very long chain fatty acids protein 6 |
| NCBI Synonym Full Names: | ELOVL fatty acid elongase 6 |
| NCBI Official Symbol: | ELOVL6 |
| NCBI Official Synonym Symbols: | FAE; LCE; FACE |
| NCBI Protein Information: | elongation of very long chain fatty acids protein 6 |
| UniProt Protein Name: | Elongation of very long chain fatty acids protein 6 |
| UniProt Synonym Protein Names: | 3-keto acyl-CoA synthase ELOVL6 |
| Protein Family: | |
| UniProt Gene Name: | ELOVL6 |
| UniProt Entry Name: | ELOV6_HUMAN |
