Description
| 抗体名: | ELOVL5 Antibody (PACO23431) |
| 抗体コード: | PACO23431 |
| サイズ: | 100ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
| 反応性: | Human |
| 免疫原: | Synthesized peptide derived from internal of human ELOVL5. |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from MCF-7 cells, using ELOVL5 antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human brain tissue using ELOVL5 antibody. |
| バックグラウンド: | Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. |
| シノニム: | Elongation of very long chain fatty acids protein 5; ELOV5; ELOVL2; hELO1; |
| UniProt Protein Function: | ELOVL5: Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. Belongs to the ELO family. |
| UniProt Protein Details: | Protein type:EC 2.3.1.199; Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 6p12.1 Cellular Component: cell soma; dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane Molecular Function:fatty acid elongase activity; protein binding Biological Process: cellular lipid metabolic process; linoleic acid metabolic process; triacylglycerol biosynthetic process; unsaturated fatty acid biosynthetic process; unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process Disease: Spinocerebellar Ataxia 38 |
| NCBI Summary: | This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014] |
| UniProt Code: | Q9NYP7 |
| NCBI GenInfo Identifier: | 74753072 |
| NCBI Gene ID: | 60481 |
| NCBI Accession: | Q9NYP7.1 |
| UniProt Secondary Accession: | Q9NYP7,Q59EL3, Q5TGH5, Q6NXE7, Q7L2S5, Q8NCG4, Q9UI22 B4DZJ2, F6SH78, |
| UniProt Related Accession: | Q9NYP7 |
| Molecular Weight: | 9,580 Da |
| NCBI Full Name: | Elongation of very long chain fatty acids protein 5 |
| NCBI Synonym Full Names: | ELOVL fatty acid elongase 5 |
| NCBI Official Symbol: | ELOVL5 |
| NCBI Official Synonym Symbols: | HELO1; SCA38; dJ483K16.1 |
| NCBI Protein Information: | elongation of very long chain fatty acids protein 5 |
| UniProt Protein Name: | Elongation of very long chain fatty acids protein 5 |
| UniProt Synonym Protein Names: | 3-keto acyl-CoA synthase ELOVL5 |
| UniProt Gene Name: | ELOVL5 |
| UniProt Entry Name: | ELOV5_HUMAN |
