Description
| 抗体名: | EIF4H Antibody (PACO09060) |
| 抗体コード: | PACO09060 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human EIF4H |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | 27kd; |
| UniProt Protein Function: | EIF4H: eukaryotic translation initiation factor 4H stimulates protein translation. May stimulate the activities of EIF4A, EIF4B and EIF4F during the steps involving mRNA binding and utilization in the initiation of protein biosynthesis. Binds mRNA. Two alternatively spliced isoforms have been described. The short isoform is the predominant isoform and is expressed alone in liver and skeletal muscle. Both isoforms are expressed in fibroblast, spleen, testis and bone marrow. Levels are high in lung and pancreas and low in heart, frontal cortex and kidney. |
| UniProt Protein Details: | Protein type:Translation initiation; Translation; RNA-binding Chromosomal Location of Human Ortholog: 7q11.23 Cellular Component: cytosol; eukaryotic translation initiation factor 4F complex; membrane; polysome Molecular Function:helicase activity; protein binding; ribosomal small subunit binding; RNA binding; RNA strand annealing activity; RNA strand-exchange activity; translation factor activity, nucleic acid binding Biological Process: formation of translation preinitiation complex; regulation of translational initiation; translational initiation Disease: Williams-beuren Syndrome |
| NCBI Summary: | This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15056 |
| NCBI GenInfo Identifier: | 18276665 |
| NCBI Gene ID: | 7458 |
| NCBI Accession: | Q15056.5 |
| UniProt Secondary Accession: | Q15056,A8K3R1, D3DXF6, D3DXF8, |
| UniProt Related Accession: | Q15056 |
| Molecular Weight: | 25,200 Da |
| NCBI Full Name: | Eukaryotic translation initiation factor 4H |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 4H |
| NCBI Official Symbol: | EIF4H |
| NCBI Official Synonym Symbols: | WSCR1; WBSCR1; eIF-4H |
| NCBI Protein Information: | eukaryotic translation initiation factor 4H |
| UniProt Protein Name: | Eukaryotic translation initiation factor 4H |
| UniProt Synonym Protein Names: | Williams-Beuren syndrome chromosomal region 1 protein |
| Protein Family: | Eukaryotic translation initiation factor |
| UniProt Gene Name: | EIF4H |
| UniProt Entry Name: | IF4H_HUMAN |
