Description
| 抗体名: | EDF1 Antibody (PACO08992) |
| 抗体コード: | PACO08992 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human EDF1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | endothelial differentiation-related factor 1;EDF1;EDF-1;MBF1;MGC9058 ; |
| UniProt Protein Function: | EDF1: Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor; DNA-binding; Nuclear receptor co-regulator; RNA-binding Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: transcription factor TFIID complex; cytoplasm; nucleolus; intracellular; nucleus Molecular Function:calmodulin binding; methyltransferase activity; protein binding; histone acetyltransferase activity; sequence-specific DNA binding; transcription coactivator activity; transcription factor activity Biological Process: endothelial cell differentiation; regulation of lipid metabolic process; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; multicellular organismal development; positive regulation of DNA binding |
| UniProt Code: | O60869 |
| NCBI GenInfo Identifier: | 62510569 |
| NCBI Gene ID: | |
| NCBI Accession: | O60869.1 |
| Molecular Weight: | ~ 16kDa |
| NCBI Full Name: | Endothelial differentiation-related factor 1 |
| UniProt Protein Name: | Endothelial differentiation-related factor 1 |
| UniProt Synonym Protein Names: | Multiprotein-bridging factor 1; MBF1 |
| Protein Family: | Endothelial differentiation-related factor |
| UniProt Gene Name: | EDF1 |
| UniProt Entry Name: | EDF1_HUMAN |
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