Description
| 抗体名: | ECI2 Antibody (PACO06438) |
| 抗体コード: | PACO06438 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human |
| 免疫原: | Synthesized peptide derived from the Internal region of human DRS-1. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of K562 cells using DRS-1 Polyclonal Antibody. |
 | Western Blot analysis of 293 cells using DRS-1 Polyclonal Antibody. |
| シノニム: | ECI2; DRS1; HCA88; PECI; Enoyl-CoA delta isomerase 2; mitochondrial; DRS-1; Delta(3),delta(2)-enoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; Diazepam-binding inhibitor-related protein 1; DBI-related protein 1; Dodecenoyl-CoA isomerase; Hep |
| UniProt Protein Function: | PECI: Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Isomerase; EC 5.3.3.8; Lipid Metabolism - fatty acid Chromosomal Location of Human Ortholog: 6p24.3 Cellular Component: intracellular membrane-bound organelle; membrane; mitochondrion; nucleoplasm; peroxisomal matrix Molecular Function:dodecenoyl-CoA delta-isomerase activity; receptor binding Biological Process: cellular lipid metabolic process |
| NCBI Summary: | This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011] |
| UniProt Code: | O75521 |
| NCBI GenInfo Identifier: | 257051079 |
| NCBI Gene ID: | 10455 |
| NCBI Accession: | O75521.4 |
| UniProt Secondary Accession: | O75521,Q5JYK5, Q5JYK7, Q7L124, Q8N0X0, Q9BUE9, Q9H0T9 Q9NQH1, Q9NYH7, Q9UN55, |
| UniProt Related Accession: | O75521 |
| Molecular Weight: | 39,609 Da |
| NCBI Full Name: | Enoyl-CoA delta isomerase 2, mitochondrial |
| NCBI Synonym Full Names: | enoyl-CoA delta isomerase 2 |
| NCBI Official Symbol: | ECI2 |
| NCBI Official Synonym Symbols: | DRS1; PECI; ACBD2; DRS-1; HCA88; dJ1013A10.3 |
| NCBI Protein Information: | enoyl-CoA delta isomerase 2, mitochondrial |
| UniProt Protein Name: | Enoyl-CoA delta isomerase 2, mitochondrial |
| UniProt Synonym Protein Names: | DRS-1; Delta(3),delta(2)-enoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; Diazepam-binding inhibitor-related protein 1; DBI-related protein 1; Dodecenoyl-CoA isomerase; Hepatocellular carcinoma-associated antigen 88; Peroxisomal 3,2-trans-enoyl-CoA isomerase; pECI; Renal carcinoma antigen NY-REN-1 |
| Protein Family: | Enoyl-CoA delta isomerase |
| UniProt Gene Name: | ECI2 |
| UniProt Entry Name: | ECI2_HUMAN |
